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Symbol Name ID |
Nos2
nitric oxide synthase 2, inducible MGI:97361 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Asthma |
| Disease(s) Associated with NOS2 | |
| asthma |
| Mouse Phenotypes | immune system phenotype |
abnormal osteoclast differentiation |
increased T cell proliferation |
decreased susceptibility to induced colitis |
pancreas inflammation |
abnormal eosinophil cell number |
decreased eosinophil cell number |
increased single-positive T cell number |
decreased osteoclast cell number |
abnormal osteoclast morphology |
increased IgG2a level |
abnormal T-helper 1 physiology |
abnormal macrophage physiology |
abnormal immune system morphology |
enlarged inguinal lymph nodes |
abnormal immune system physiology |
abnormal adaptive immunity |
increased interferon-gamma secretion |
increased susceptibility to experimental autoimmune encephalomyelitis |
abnormal inflammatory response |
decreased susceptibility to endotoxin shock |
decreased inflammatory response |
increased inflammatory response |
skin inflammation |
abnormal response to infection |
increased susceptibility to bacterial infection |
increased susceptibility to parasitic infection |
increased length of allograft survival |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||||
| Nos2tm1Lau/Nos2tm1Lau | * | ||||||||||||||||||||||||||||
| Nos2tm1Liew/Nos2tm1Liew | * | ||||||||||||||||||||||||||||
| Nos2tm1Mrl/Nos2tm1Mrl | |||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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